Selected project
Scn1a_KI
Graphics
Graphic caption: Open Field: Center - Permanence time boxplot with stripchart, split by sex and genotype
Graphic caption: Open Field: Distance Traveled, average plot, split by sex and genotype
Graphic caption: Open Field: Distance in the center, average plot, split by sex and genotype
Graphic caption: Open Field: Distance traveled - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Open Field: Number of rears - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Open Field: Number of rears, average plot, split by sex and genotype
Graphic caption: Open Field: Percent center distance - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Open Field: Percent time spent in the center - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Prepulse Inhibition: PPIgrouped barplot, split by sex and genotype
Graphic caption: Prepulse Inhibition: Startle amplitude - ST110 boxplot, split by sex and genotype
Tables
Table caption: Acoustic startle: Means, standard deviation and p-values calculated by a linear model
femalemalelinear modellinear modellinear model
 controlmutantcontrolmutantgenotypesexgenotype:sex
 n=15n=15n=11n=15   
 mean ± sdmean ± sdmean ± sdmean ± sdp-valuep-valuep-value
Startle amplitude - BN 15.22 ± 6.4820.18 ± 4.5916.14 ± 4.122.59 ± 4.93< 0.0010.2380.594
Startle amplitude - P1 43.37 ± 11.7745.4 ± 12.4349.3 ± 16.347.21 ± 11.440.9930.2690.554
Startle amplitude - P2 53.06 ± 15.7549.62 ± 12.3157.79 ± 13.2553.03 ± 11.770.2610.2640.856
Startle amplitude - P3 66.46 ± 17.9365.91 ± 16.8489.2 ± 30.6277.96 ± 22.840.3250.0050.372
Startle amplitude - P4 132.75 ± 64.67136.24 ± 54.55161.19 ± 60.67170.34 ± 61.910.70.0610.863
Startle amplitude - ST110 495.37 ± 177.4539.67 ± 184.98773.04 ± 256.44658.99 ± 192.460.5220.0010.15
Startle amplitude - PP67 293.6 ± 137.22338.57 ± 144.21410.4 ± 228.88373.41 ± 148.720.9280.0910.357
Startle amplitude - PP69 266.46 ± 130.15312.97 ± 115.87390.44 ± 198.12334.53 ± 144.80.9060.0710.2
Startle amplitude - PP73 220.35 ± 96.75254.08 ± 107.93306.47 ± 160.81256.45 ± 124.970.8050.1840.208
Startle amplitude - PP81 181.4 ± 67.88200.53 ± 68.25263.55 ± 133.18217.47 ± 58.830.5480.0310.15
Prepulse inhibition - PP67 41.17 ± 15.4638.33 ± 12.249.77 ± 1742.49 ± 19.820.2550.1530.616
Prepulse inhibition - PP69 47.46 ± 12.641.43 ± 11.4751.64 ± 14.9648.47 ± 17.560.2380.1520.712
Prepulse inhibition - PP73 55.81 ± 10.1753.63 ± 9.2162.52 ± 12.8360.85 ± 13.780.540.030.934
Prepulse inhibition - PP81 62.34 ± 8.9261.79 ± 8.1167.09 ± 10.8365.55 ± 9.590.6790.0960.844
Prepulse inhibition - Global 51.69 ± 10.6648.78 ± 8.7757.74 ± 13.3154.35 ± 13.860.3240.0710.94
Body weight ASPPI 19.67 ± 1.1119.4 ± 1.3726.72 ± 2.3424.49 ± 1.550.005< 0.0010.027
Startle amplitude - BN /bw 0.78 ± 0.341.03 ± 0.240.6 ± 0.170.92 ± 0.21< 0.0010.0430.693
Startle amplitude - P1 /bw 2.21 ± 0.632.35 ± 0.721.83 ± 0.531.93 ± 0.440.4650.0140.86
Startle amplitude - P2 /bw 2.71 ± 0.862.57 ± 0.672.15 ± 0.482.16 ± 0.430.6420.0080.667
Startle amplitude - P3 /bw 3.41 ± 0.973.41 ± 0.843.32 ± 1.023.19 ± 0.850.760.5460.745
Startle amplitude - P4 /bw 6.83 ± 3.566.99 ± 2.656.08 ± 2.316.97 ± 2.610.4880.6250.639
Table caption: Open Field: Means, standard deviation and p-values calculated by a linear model
femalemaleLinear modelLinear modelLinear model
 controlmutantcontrolmutantgenotypesexgenotype:sex
 n=15n=15n=12n=15   
 mean ± sdmean ± sdmean ± sdmean ± sdp-valuep-valuep-value
Distance traveled - 5 min 7234.2 ± 1390.57390.9 ± 1240.96494.8 ± 12557311.1 ± 1000.70.1430.2160.318
Distance traveled - 10 min 6496.9 ± 1189.37075.2 ± 1259.46344 ± 924.56424.9 ± 614.50.2360.150.37
Distance traveled - 15 min 6164.3 ± 15596535 ± 1627.35407.1 ± 1124.26043.5 ± 1292.90.1920.1070.728
Distance traveled - 20 min 5827.5 ± 14776146.9 ± 1900.54954.4 ± 1297.66153.1 ± 1010.50.0570.2720.265
Distance traveled - Total 25722.8 ± 4851.127148 ± 5508.323200.3 ± 4091.225932.6 ± 3168.90.0890.1260.589
Number of rears - 5 min 33.6 ± 8.837.9 ± 8.935.9 ± 6.739.2 ± 5.50.0690.3740.81
Number of rears - 10 min 36.9 ± 11.749.4 ± 9.745.3 ± 10.946 ± 8.60.0190.3580.034
Number of rears - 15 min 36.6 ± 10.146.9 ± 6.140.4 ± 10.942.3 ± 7.20.0110.8550.072
Number of rears - 20 min 34.5 ± 1144.7 ± 10.735.2 ± 10.544.6 ± 7.50.0010.9060.886
Number of rears - Total 141.5 ± 36.9178.6 ± 25156.7 ± 32.6171.7 ± 21.90.0020.6010.167
Percent center distance - 5 min 27.6 ± 8.233.8 ± 4.419.4 ± 930.1 ± 4.6< 0.0010.0010.218
Percent center distance - 10 min 35.7 ± 14.937.1 ± 1028.1 ± 11.833.9 ± 10.50.2640.0950.503
Percent center distance - 15 min 40.6 ± 13.336.5 ± 10.123.4 ± 10.635.1 ± 14.70.2560.0070.021
Percent center distance - 20 min 33.8 ± 17.432.2 ± 12.521.8 ± 13.432.2 ± 13.20.2510.1220.119
Percent center distance - Total 34.6 ± 11.835.3 ± 6.823.5 ± 7.633 ± 8.80.0390.0080.073
Percent time spent in the center - 5 min 23.5 ± 8.632.7 ± 6.715.3 ± 9.525 ± 7.3< 0.001< 0.0010.893
Percent time spent in the center - 10 min 31.7 ± 15.133.8 ± 12.623.5 ± 11.730 ± 13.10.2310.0980.532
Percent time spent in the center - 15 min 35 ± 13.833 ± 10.318.1 ± 10.730.6 ± 15.80.1350.0070.042
Percent time spent in the center - 20 min 30.4 ± 18.828.2 ± 12.117.6 ± 1427.6 ± 13.20.3270.0960.127
Percent time spent in the center - Total 30.1 ± 12.531.9 ± 818.6 ± 8.228.3 ± 10.50.0380.0070.146
Whole Arena - resting time 153.2 ± 55.2190 ± 40.9106.8 ± 31.7145.6 ± 22.30.001< 0.0010.924
Whole Arena - Permanence time 1200 ± 01200 ± 01200 ± 01200 ± 0NANANA
Whole Arena - average speed 24.7 ± 5.226.9 ± 5.221.3 ± 4.124.6 ± 3.30.0270.0230.613
Periphery - distance 16465.8 ± 278717508.1 ± 3694.617676.2 ± 3358.917196.4 ± 1910.40.7260.5750.344
Periphery - resting time 109.5 ± 34.5131 ± 26.990.3 ± 27.4107.6 ± 13.90.0080.0040.768
Periphery - Permanence time 838.4 ± 150.1817.1 ± 95.8976.3 ± 98860.4 ± 126.10.0370.0070.146
Periphery - average speed 23.4 ± 5.125.7 ± 5.220.1 ± 3.923.3 ± 3.50.0280.0220.736
Center - distance 9257 ± 4031.39639.9 ± 2792.35524.1 ± 2105.28736.2 ± 3042.10.0350.0070.094
Center - resting time 43.8 ± 3359 ± 28.516.4 ± 14.638 ± 20.20.0090.0010.649
Center - Permanence time 361.6 ± 150382.9 ± 95.8223.7 ± 98339.6 ± 126.10.0370.0070.146
Center - average speed 28.4 ± 4.729.8 ± 5.227.4 ± 4.829.4 ± 3.70.1710.5440.789
Latency to enter in the center 13.7 ± 148.3 ± 13.423 ± 16.611.3 ± 10.80.0230.10.392
Number of entries in the center 360.3 ± 117.9385 ± 88230.2 ± 74.7342.5 ± 87.70.0090.0010.087
Whole arena - distance 25722.8 ± 4851.127148 ± 5508.323200.3 ± 4091.225932.6 ± 3168.90.0890.1260.589
Media files
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