Selected project
Prox2-em1 / CRISPR/Cas
Graphics
Graphic caption: Flow cytometry spleen IMPC: Spleen weight boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: T cells (panel A) boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: NKT cells (panel A) boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: NK cells (panel A) boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DP Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD25+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD25+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD25+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD25+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD25+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD25+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4pos T cell subsets, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44+CD62L-Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44+CD62L+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44-CD62L+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44-CD62L-Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8pos T cell subsets, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44+CD62L-Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44+CD62L+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44-CD62L+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44-CD62L-Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44+CD62L-Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44+CD62L+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44-CD62L+Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44-CD62L-Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44+CD62L-NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44+CD62L+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD4 CD44-CD62L+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44+CD62L-NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44+CD62L+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: CD8 CD44-CD62L+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44+CD62L-NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44+CD62L+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: DN CD44-CD62L+NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: Neutrophils boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: Monocytes boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: Eosinophils boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: B cells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: B1B cells boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: Follicular B cells (CD21/35+) boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: pre- B cells (CD21/35 low) boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: MZB (CD21/35high) boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: cDCs boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: cDCs CD11b Type boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: pDCs IMPC boxplot with stripchart, split by sex and genotype
Graphic caption: Flow cytometry spleen IMPC: RP Macrophage (CD19-CD11c-) boxplot with stripchart, split by sex and genotype
Tables
Table caption: Flow cytometry spleen IMPC: NKT cell subsets; Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test
femalemalefemalemaleoverall
 conmutconmut   
 n=7n=3n=5n=3   
 median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-valuep-valuep-value
CD4 NKTcells 48.82
[47.33 , 56.97]
46.48
[44.99 , 46.64]
48.45
[41.41 , 50.92]
41.95
[41.12 , 42.66]
0.1170.5710.067
CD8 NKTcells 17.47
[16.22 , 19.55]
21.34
[20.8 , 22.82]
19.45
[16.59 , 20.41]
22.8
[21.71 , 23.45]
0.1170.250.026
DN NKTcells 28.97
[25.23 , 31.61]
29.46
[29.09 , 30.07]
30.98
[30.3 , 33.75]
32.46
[31.52 , 34.64]
10.5710.75
CD4 CD25+NKTcells 3.49
[3.1 , 4.47]
5.48
[4.95 , 5.8]
5.07
[5 , 5.12]
5.57
[5.26 , 6.11]
0.0670.5710.024
CD4 CD25-NKTcells 96.51
[95.61 , 96.9]
94.52
[94.2 , 95.06]
95
[94.88 , 95.02]
94.43
[93.89 , 94.78]
0.0670.5710.026
CD8 CD25+NKTcells 0.85
[0.59 , 1.12]
0.48
[0.42 , 0.7]
0.39
[0.25 , 0.57]
0.55
[0.43 , 0.62]
0.5170.7860.616
CD8 CD25-NKTcells 99.15
[98.88 , 99.41]
99.52
[99.52 , 99.53]
99.61
[99.43 , 99.75]
99.45
[99.38 , 99.8]
0.38310.385
DN CD25+NKTcells 1.6
[1.27 , 1.72]
2.42
[2.23 , 2.44]
1.79
[1.64 , 2.64]
2.21
[2.14 , 2.62]
0.1170.3930.067
DN CD25-NKTcells 98.4
[98.28 , 98.72]
97.85
[97.72 , 98]
98.03
[97.36 , 98.36]
97.79
[97.39 , 97.86]
0.1170.3930.083
CD4 CD44+CD62L-NKTcells 73.77
[71.17 , 78.55]
67.09
[66.08 , 68.48]
70.62
[65.54 , 72.54]
67.32
[64.34 , 67.67]
0.0670.3930.032
CD4 CD44+CD62L+NKTcells 21.34
[19.86 , 22.04]
24.26
[23.77 , 24.57]
22.46
[20.98 , 25.73]
26.21
[25.27 , 28.17]
0.0330.250.013
CD4 CD44-CD62L+NKTcells 2.37
[1.47 , 5.16]
6.65
[6.17 , 8.14]
6.57
[4.22 , 7.12]
6.77
[6.2 , 7.01]
0.1170.7860.102
CD8 CD44+CD62L-NKTcells 5.2
[4.62 , 5.51]
8.86
[7.58 , 9.32]
6.93
[6.35 , 7.05]
6.83
[5.18 , 7.77]
0.03310.18
CD8 CD44+CD62L+NKTcells 81.52
[72.19 , 83.8]
69.77
[67.4 , 71.55]
75.93
[70.67 , 76.89]
74.92
[72.72 , 77.06]
0.18310.213
CD8 CD44-CD62L+NKTcells 13.12
[10.62 , 20.23]
19.34
[19.25 , 22.61]
17.51
[16.17 , 21.14]
19.52
[16.48 , 19.99]
0.38310.335
DN CD44+CD62L-NKTcells 47.92
[44.92 , 50.46]
45.08
[41.62 , 45.5]
50.99
[47.1 , 55.39]
43.58
[42.66 , 44.41]
0.1830.250.032
DN CD44+CD62L+NKTcells 45.35
[44.5 , 47.58]
45.74
[44.26 , 48.2]
41.93
[39.24 , 43.87]
49.06
[48.13 , 49.2]
0.6670.250.18
DN CD44-CD62L+NKTcells 5.52
[0.74 , 6.53]
7.65
[6.53 , 8.29]
3.95
[3.68 , 5.53]
5.98
[4.42 , 6.3]
0.1830.5710.125
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