Selected project
Hmgn5
Graphics
Graphic caption: Flow Cytometry: FACS pie chart, split by sex and genotype
Tables
Table caption: Flow Cytometry: Frequencies of Leukocyte subpopulations in peripheral blood after erythrocyte lysis [percentage of all leukocytes (CD45+ cells), or corresponding parent gate, respectively]. Means, standard deviation and p-values calculated by a linear model
femalemaleLinear modelLinear modelLinear model
 controlmutantcontrolmutantgenotypesexgenotype:sex
 n=10n=10n=10n=10   
 mean ± sdmean ± sdmean ± sdmean ± sdp-valuep-valuep-value
CD45+/T cells 20.61 ± 3.2122.51 ± 5.3614.29 ± 2.116.94 ± 3.180.057< 0.0010.748
CD45+/CD3+CD4+ 10.31 ± 2.1111.35 ± 3.287.49 ± 1.338.7 ± 1.820.124< 0.0010.904
CD45+/CD3+CD8+ 9.64 ± 1.2310.24 ± 2.036.36 ± 0.847.67 ± 1.30.04< 0.0010.432
CD45+/B cells 40.75 ± 3.3737.73 ± 3.0254.93 ± 3.4154.78 ± 2.960.126< 0.0010.164
CD45+/CD5-NK+ 4.91 ± 0.734.48 ± 0.983.17 ± 0.623.03 ± 0.490.231< 0.0010.528
CD45+/CD11b+Gr1+ 19.78 ± 3.2616.13 ± 4.0814.27 ± 2.4412.11 ± 20.005< 0.0010.445
CD45+/NK-Gr1-CD11b+ 2.92 ± 0.463.82 ± 1.173.11 ± 0.712.92 ± 0.460.1460.1470.03
CD3+CD4+/CD25+ 5.62 ± 0.85.54 ± 0.976.18 ± 0.86.26 ± 0.920.9910.0260.786
CD45+/CD3+gammadeltaTCR+ 0.41 ± 0.060.42 ± 0.060.26 ± 0.030.28 ± 0.020.206< 0.0010.513
CD3+CD4+/CD62L+ 54.17 ± 11.5548.35 ± 17.5837.06 ± 11.2848.47 ± 17.530.5540.0780.074
CD3+CD4+/CD44+ 62.03 ± 3.2163.63 ± 5.6555.96 ± 3.1757.35 ± 4.620.278< 0.0010.939
CD3+CD8+/CD62L+ 67.85 ± 7.8164 ± 16.9447.76 ± 9.7461.36 ± 18.160.2750.0140.055
CD3+CD8+/CD44+ 52.91 ± 4.4353.52 ± 4.6750.98 ± 2.6352.34 ± 2.850.4130.1990.754
CD45+/CD5+NK+ 0.35 ± 0.050.4 ± 0.070.26 ± 0.050.26 ± 0.040.282< 0.0010.144
B cells/IgD+ 88.48 ± 2.4989.53 ± 2.0291.25 ± 1.992.27 ± 1.220.104< 0.0010.981
B cells/CD5+ 1.16 ± 0.241.3 ± 0.250.86 ± 0.190.9 ± 0.190.203< 0.0010.544
B cells/B220+MHCclassII+ 92.09 ± 0.891.41 ± 1.5493.44 ± 1.2593.46 ± 1.480.427< 0.0010.4
NK+/CD11b+ 71.55 ± 5.1170.55 ± 3.6156.71 ± 6.4655.69 ± 5.630.551< 0.0010.995
CD3+ rest 0.66 ± 0.110.92 ± 0.280.44 ± 0.060.57 ± 0.180.001< 0.0010.231
CD45+/CD3+CD4+CD25+ 0.58 ± 0.140.61 ± 0.160.47 ± 0.110.54 ± 0.10.1930.0270.666
ratio CD4:CD8 1.06 ± 0.141.09 ± 0.121.18 ± 0.121.13 ± 0.090.7960.0580.368
ratio Granulocytes:(Tcells+B cells) 0.32 ± 0.070.27 ± 0.090.21 ± 0.050.17 ± 0.030.035< 0.0010.73
ratio Tcells:Bcells 0.51 ± 0.110.61 ± 0.170.26 ± 0.050.31 ± 0.070.044< 0.0010.51
Table caption: Flow Cytometry: Frequencies of Leukocyte subpopulations in peripheral blood after erythrocyte lysis [percentage of all leukocytes (CD45+ cells), or corresponding parent gate, respectively]. Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
femalemalefemalemaleoverall
 controlmutantcontrolmutant   
 n=10n=10n=10n=10   
 median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-valuep-valuep-value
CD45+/T cells 20.9
[18.75 , 21.43]
23.25
[17.98 , 26.02]
14.7
[13.43 , 15.6]
17.4
[14.43 , 19.55]
0.280.0750.185
CD45+/CD3+CD4+ 10.2
[9.16 , 11.3]
11.7
[8.6 , 13.5]
7.62
[6.9 , 8.32]
8.96
[7.22 , 10.24]
0.4030.1430.256
CD45+/CD3+CD8+ 9.81
[8.79 , 10.59]
10.7
[8.56 , 11.78]
6.46
[5.96 , 6.82]
7.9
[6.64 , 8.52]
0.3050.0290.14
CD45+/B cells 40.15
[38.85 , 42.85]
37.5
[35.25 , 38.83]
55.3
[53.9 , 56.55]
54.2
[53.1 , 55.12]
0.0450.3420.292
CD45+/CD5-NK+ 4.83
[4.39 , 5.41]
4.52
[3.73 , 4.94]
3.16
[2.83 , 3.43]
2.98
[2.66 , 3.25]
0.280.5290.341
CD45+/CD11b+Gr1+ 20.4
[18.7 , 20.57]
14.85
[13.95 , 16.65]
13.5
[12.9 , 14.57]
12.1
[10.47 , 12.5]
0.0170.0270.013
CD45+/NK-Gr1-CD11b+ 2.75
[2.58 , 3.19]
3.49
[3.25 , 3.84]
2.96
[2.64 , 3.38]
2.99
[2.58 , 3.29]
0.0110.7560.14
CD3+CD4+/CD25+ 5.47
[5.17 , 5.89]
5.24
[4.78 , 6.17]
6.05
[5.66 , 6.79]
6.25
[5.49 , 6.67]
0.68410.764
CD45+/CD3+gammadeltaTCR+ 0.42
[0.41 , 0.45]
0.42
[0.39 , 0.46]
0.26
[0.25 , 0.27]
0.29
[0.28 , 0.3]
0.8690.0140.279
CD3+CD4+/CD62L+ 59.3
[54.52 , 60.17]
53.25
[49.33 , 56.65]
31.5
[29.93 , 46.02]
54.65
[31.3 , 59.15]
0.1380.2250.846
CD3+CD4+/CD44+ 62.2
[59.4 , 64.45]
61.85
[59.73 , 65.45]
55.9
[54.08 , 58.25]
56.8
[53.88 , 60.55]
0.6990.5290.482
CD3+CD8+/CD62L+ 69.7
[67.33 , 72.72]
69.45
[65.55 , 72.33]
42.05
[40.62 , 56.77]
66.95
[48.92 , 74.67]
0.8690.0520.204
CD3+CD8+/CD44+ 51.95
[50.62 , 53.67]
51.65
[50.35 , 55.05]
51.25
[50.12 , 52.25]
53.85
[50.42 , 54.08]
0.9850.2250.41
CD45+/CD5+NK+ 0.35
[0.31 , 0.38]
0.42
[0.34 , 0.44]
0.26
[0.23 , 0.29]
0.24
[0.23 , 0.26]
0.1580.5380.784
B cells/IgD+ 89.15
[87.12 , 90.08]
89.65
[88.85 , 91.12]
90.95
[89.83 , 91.45]
92.4
[91.83 , 92.95]
0.3430.0930.106
B cells/CD5+ 1.19
[0.97 , 1.34]
1.21
[1.12 , 1.36]
0.85
[0.75 , 1.02]
0.88
[0.76 , 1.02]
0.3250.8110.372
B cells/B220+MHCclassII+ 92.1
[91.6 , 92.67]
91.85
[90.85 , 92.38]
93.25
[92.9 , 93.97]
93.6
[92.67 , 94.55]
0.4230.7540.753
NK+/CD11b+ 71.45
[67.25 , 75.53]
71.85
[67.97 , 72.72]
56.9
[51 , 60.02]
55.65
[52.52 , 57.65]
0.70.6840.763
CD3+ rest 0.68
[0.56 , 0.74]
0.83
[0.8 , 0.98]
0.44
[0.4 , 0.46]
0.52
[0.49 , 0.65]
0.0070.0550.018
CD45+/CD3+CD4+CD25+ 0.58
[0.46 , 0.63]
0.6
[0.48 , 0.7]
0.49
[0.44 , 0.53]
0.57
[0.45 , 0.6]
0.6310.1230.265
ratio CD4:CD8 1.04
[1.02 , 1.05]
1.08
[0.99 , 1.18]
1.17
[1.12 , 1.2]
1.12
[1.09 , 1.16]
0.7520.3050.952
ratio Granulocytes:(Tcells+B cells) 0.32
[0.3 , 0.34]
0.24
[0.23 , 0.31]
0.2
[0.18 , 0.21]
0.16
[0.14 , 0.18]
0.0780.0540.066
ratio Tcells:Bcells 0.5
[0.43 , 0.56]
0.6
[0.5 , 0.73]
0.26
[0.24 , 0.3]
0.32
[0.27 , 0.36]
0.210.1040.256
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