Selected project
Dnmt3l / HEPD0801_1_E06-tm1b
Graphics
Graphic caption: Clinical Chemistry: Potassium boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Clinical Chemistry: Albumin boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Clinical Chemistry: Total protein boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Clinical Chemistry: Urea boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Clinical Chemistry: Chloride boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Clinical Chemistry: Sodium boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Clinical Chemistry: Creatinine enz. boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Red blood cell boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: White blood cell boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Hemoglobin boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Hematocrit boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Platelet boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Mean corpuscular volume boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Mean corpuscular hemoglobin content boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Mean corpuscular hemoglobin concentration boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Mean platelets volume boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Hematology: Distribution index of red blood cells boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: IpGTT: Body mass loss vs. body weight before food withdrawal
Graphic:
Graphic caption: IpGTT: Blood glucose concentration average plot, split by genotype and sex
Graphic:
Graphic caption: IpGTT: Glucose (T=0) boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: IpGTT: AUC 0-30 boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: IpGTT: AUC 30-120 boxplot with stripchart, split by sex and genotype
Graphic:
Tables
Table caption: Clinical Chemistry: Means, Standard deviations and p-values of a Wilcoxon test.
Table:
female
male
female
male
overall
con
mut
con
mut
n=11
n=9
n=11
n=10
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
Sodium [mmol/l]
152
[149 , 154]
151
[148 , 154]
153
[152 , 155]
153
[152 , 155]
0.729
0.731
0.749
Potassium [mmol/l]
4.1
[3.9 , 4.2]
4.2
[3.9 , 4.3]
4.5
[4.2 , 4.5]
4.6
[4.4 , 4.6]
0.955
0.118
0.347
Chloride [mmol/l]
112.6
[112.2 , 113.9]
112.9
[111.4 , 114.1]
112
[111.4 , 112.7]
111.2
[110.1 , 112.7]
0.882
0.5
0.374
Total protein [g/l]
53.4
[52 , 54.5]
52
[51.2 , 55.2]
54.2
[52.8 , 55.4]
51.6
[50.5 , 52.1]
0.4
0.061
0.044
Albumin [g/l]
27.9
[27.4 , 28.8]
27.9
[26.7 , 29.2]
27.5
[26.3 , 28.1]
25.6
[25.1 , 26.4]
0.781
0.021
0.064
Creatinine enz. [µmol/l]
8.57
[8.18 , 9.2]
8.66
[7.87 , 9.19]
7.34
[6.99 , 7.96]
7.69
[7.23 , 9.04]
0.491
0.34
0.732
Urea [mmol/l]
9.99
[9.19 , 10.91]
10.82
[8.81 , 11.61]
10.76
[9.1 , 11.38]
10.06
[9.06 , 12.04]
0.766
0.931
0.912
Table caption: Hematology: Values measured in EDTA-blood samples. Means, standard deviations and p-values for genotype, sex and genotype $ imes$ sex interaction effects calculated by a linear model.
Table:
female
male
linear model
linear model
linear model
con
mut
con
mut
genotype
sex
genotype:sex
n=11
n=9
n=11
n=10
mean ± sd
mean ± sd
mean ± sd
mean ± sd
p-value
p-value
p-value
RBC [Mio/mm³]
10.58 ± 0.38
10.58 ± 0.24
11.14 ± 0.46
10.73 ± 0.47
0.11
0.008
0.112
HGB [g/dl]
16.36 ± 0.72
16.84 ± 0.49
17.15 ± 0.55
16.78 ± 0.35
0.741
0.046
0.02
HCT [%]
50.84 ± 2.12
51.38 ± 0.81
53.69 ± 2.01
51.33 ± 1.51
0.102
0.014
0.011
MCV [fl]
48 ± 1.1
48.44 ± 1.24
48.09 ± 0.83
48 ± 0.94
0.587
0.587
0.412
MCH [pg]
15.45 ± 0.37
15.92 ± 0.51
15.41 ± 0.4
15.66 ± 0.57
0.018
0.295
0.459
MCHC [g/dl]
32.2 ± 0.72
32.79 ± 0.81
31.95 ± 0.73
32.69 ± 0.69
0.007
0.46
0.752
RDW [%]
13.76 ± 0.46
13.76 ± 0.48
14.26 ± 0.61
14.44 ± 0.66
0.634
0.002
0.602
WBC [10³/mm³]
8.57 ± 1.62
8.16 ± 1.58
10.96 ± 1.95
10.98 ± 2.74
0.754
< 0.001
0.735
PLT [10³/mm³]
845.82 ± 157.12
783.78 ± 174.68
989 ± 258.25
1001.3 ± 239.45
0.711
0.01
0.58
MPV [fl]
6.23 ± 0.14
6.38 ± 0.1
6.28 ± 0.18
6.3 ± 0.16
0.081
0.806
0.168
PDW [fL]
5.54 ± 0.2
5.71 ± 0.06
5.52 ± 0.14
5.56 ± 0.16
0.029
0.084
0.171
PLCR [%]
2.19 ± 0.51
2.48 ± 0.61
2.59 ± 1.07
2.53 ± 0.67
0.636
0.345
0.467
PCT [%]
0.53 ± 0.1
0.5 ± 0.11
0.62 ± 0.16
0.63 ± 0.15
0.871
0.01
0.607
Table caption: IpGTT: Basal glucose level and area under the curve (AUC) for the first 30 minutes and the remaining 90 minutes of the test obtained from glucose tolerance testing: Means, standard deviation and p-values calculated by a linear model.
Table:
female
male
linear model
linear model
linear model
con
mut
con
mut
genotype
sex
genotype:sex
n=11
n=9
n=11
n=10
mean ± sd
mean ± sd
mean ± sd
mean ± sd
p-value
p-value
p-value
Glucose (T=0)
5.2 ± 0.59
5.13 ± 0.61
5.37 ± 0.43
5.8 ± 0.63
0.333
0.024
0.171
AUC 0-30
348.5 ± 77.1
296.1 ± 59.02
a
382.76 ± 66.28
368.84 ± 97.39
0.185
0.036
0.438
AUC 30-120
505.08 ± 170.78
414.15 ± 73.26
a
733.39 ± 114.09
714.21 ± 130.38
0.194
< 0.001
0.394
Media files
No records found.