Selected project
Pepd / Pepdtm1b(KOMP)Wtsi
Graphics
Graphic caption: Open field: Distance Traveled, average plot, split by genotype and sex
Graphic caption: Open field: Distance traveled - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Open field: Number of rears, average plot, split by genotype and sex
Graphic caption: Open field: Number of rears - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Open field: Distance in the center, average plot, split by genotype and sex
Graphic caption: Open field: Percent center distance - Total boxplot with stripchart, split by sex and genotype
Graphic caption: Open field: Center - Permanence time boxplot with stripchart, split by sex and genotype
Graphic caption: Prepulse Inhibition: PPIgrouped barplot, split by sex and genotype
Graphic caption: Acoustic startle: Acoustic startle reactivity / Body weight individuum plot, split by genotype and sex
Graphic caption: Prepulse Inhibition: Startle amplitude - ST110 boxplot with stripchart, split by sex and genotype
Tables
Table caption: Open field: Means, standard deviation and p-values calculated by a linear model
femalemalelinear modellinear modellinear model
 conmutconmutgenotypesexgenotype:sex
 n=9n=9n=10n=10   
 mean ± sdmean ± sdmean ± sdmean ± sdp-valuep-valuep-value
Distance traveled - 5 min 8046.4 ± 1311.46580.4 ± 1448.16593.5 ± 1477.37165.2 ± 911.70.2980.3120.022
Distance traveled - 10 min 6468.5 ± 996.35659.6 ± 1185.55315.6 ± 1073.45456 ± 973.60.3380.0570.176
Distance traveled - 15 min 5867.9 ± 752.64796 ± 843.95049 ± 10264546 ± 8000.0080.0660.319
Distance traveled - 20 min 5290.6 ± 1246.24563.4 ± 11784613.8 ± 888.34393.2 ± 824.20.170.2180.458
Distance traveled - Total 25673.4 ± 346121599.5 ± 3890.721572 ± 3808.321560.5 ± 2685.10.080.0760.082
Number of rears - 5 min 30.4 ± 11.613.4 ± 6.433.2 ± 9.925.6 ± 5.6< 0.0010.0130.106
Number of rears - 10 min 29.6 ± 12.715.9 ± 7.335.6 ± 10.828.8 ± 8.40.0030.0060.297
Number of rears - 15 min 29.7 ± 12.712.6 ± 532.8 ± 8.323.9 ± 8.3< 0.0010.0180.168
Number of rears - 20 min 26.3 ± 8.916.2 ± 7.530.1 ± 9.820.7 ± 7.10.0010.1410.897
Number of rears - Total 116 ± 38.758.1 ± 21.1131.3 ± 35.998.6 ± 26.1< 0.0010.010.224
Percent center distance - 5 min 21.1 ± 7.813.9 ± 4.228.2 ± 1123.4 ± 5.50.0210.0020.627
Percent center distance - 10 min 24.3 ± 8.516.5 ± 7.625.6 ± 824.3 ± 9.50.1070.1090.247
Percent center distance - 15 min 19.5 ± 59.2 ± 3.818.4 ± 7.315 ± 80.0020.2590.105
Percent center distance - 20 min 22.2 ± 912.5 ± 6.215.8 ± 9.413.9 ± 10.40.0530.390.186
Percent center distance - Total 22 ± 5.213.5 ± 4.322.9 ± 6.419.9 ± 5.90.0030.050.135
Whole Arena - resting time 94.1 ± 3548.1 ± 33.796.2 ± 2674.6 ± 26.80.0020.1590.225
Whole Arena - Permanence time 1200 ± 01200 ± 01200 ± 01200 ± 0NANANA
Whole Arena - average speed 23.3 ± 3.518.8 ± 3.519.6 ± 3.519.2 ± 2.40.0270.1220.06
Periphery - distance 19886.8 ± 181618755.3 ± 3749.916467.4 ± 2192.617163.9 ± 1477.40.7850.0030.256
Periphery - resting time 78.8 ± 30.845.1 ± 28.977.8 ± 18.766 ± 25.60.0110.2490.207
Periphery - Permanence time 994.7 ± 80.71115.9 ± 28.2971.5 ± 75.51021.3 ± 86.60.0010.0170.137
Periphery - average speed 22 ± 3.817.6 ± 3.518.6 ± 3.218.1 ± 2.50.0270.1890.068
Center - distance 5786.6 ± 2017.12844.2 ± 761.85104.6 ± 2092.94396.5 ± 1761.10.0030.450.058
Center - resting time 15.3 ± 8.33.1 ± 5.218.3 ± 10.58.6 ± 8.2< 0.0010.1240.647
Center - Permanence time 205.3 ± 80.784.1 ± 28.2228.5 ± 75.5178.6 ± 86.60.0010.0170.137
Center - average speed 31.3 ± 4.236.1 ± 5.524.1 ± 4.527.5 ± 6.80.026< 0.0010.679
Latency to enter in the center 16.9 ± 10.8a17.9 ± 15.625.2 ± 48.610.8 ± 5.80.4570.9430.395
Number of entries in the center 290.6 ± 94139.1 ± 35.9257 ± 92.7193.6 ± 62.9< 0.0010.6720.082
Whole arena - distance 25673.4 ± 346121599.5 ± 3890.721572 ± 3808.321560.5 ± 2685.10.080.0760.082
Table caption: Acoustic startle: Means, standard deviation and p-values calculated by a linear model
femalemalelinear modellinear modellinear model
 conmutconmutgenotypesexgenotype:sex
 n=9n=9n=9n=10   
 mean ± sdmean ± sdmean ± sdmean ± sdp-valuep-valuep-value
Startle amplitude - BN 21.91 ± 4.9622.17 ± 6.8121.98 ± 2.9324.31 ± 5.330.4550.5230.548
Startle amplitude - P1 46.34 ± 13.8271.71 ± 39.7245.4 ± 4.8567.53 ± 16.90.0030.7330.829
Startle amplitude - P2 48.56 ± 14.5178.86 ± 39.249.49 ± 10.2591.02 ± 50.370.0030.560.617
Startle amplitude - P3 59.67 ± 13.8599.99 ± 49.8360.33 ± 13.09115.55 ± 60.210.0010.5520.585
Startle amplitude - P4 114.91 ± 46.21230.78 ± 71.87130.47 ± 36.62212.59 ± 104.02< 0.0010.9550.476
Startle amplitude - ST110 710.54 ± 277.11780.19 ± 132.91880.12 ± 252.19908.35 ± 221.270.5180.0550.784
Startle amplitude - PP67 414.34 ± 163.46488.49 ± 138.59423.79 ± 175.99467.46 ± 169.910.280.9150.778
Startle amplitude - PP69 383.52 ± 144.78452.16 ± 94.97401.13 ± 201.13467.65 ± 183.630.2140.7580.984
Startle amplitude - PP73 315.03 ± 133.07396.2 ± 122.14286.03 ± 123.08390.63 ± 157.150.0450.70.794
Startle amplitude - PP81 228.96 ± 80.62310.54 ± 73.31224.21 ± 84.1317.5 ± 109.80.0050.970.843
Prepulse inhibition - PP67 39.98 ± 11.9737.64 ± 11.3852.77 ± 12.2749.78 ± 8.630.4710.0020.929
Prepulse inhibition - PP69 43.91 ± 12.9341.98 ± 7.4755.81 ± 14.1349.95 ± 10.040.3070.0120.604
Prepulse inhibition - PP73 54.62 ± 9.2949.97 ± 7.6467.72 ± 10.2557.99 ± 9.610.0240.0010.411
Prepulse inhibition - PP81 65.02 ± 12.3459.86 ± 8.7274.47 ± 6.5765.02 ± 9.070.0240.0240.494
Prepulse inhibition - Global 50.89 ± 10.7447.38 ± 6.8662.69 ± 10.1255.7 ± 8.250.0890.0020.565
Body weight ASPPI 20.62 ± 1.3318.5 ± 1.7825.82 ± 1.722.21 ± 2.14< 0.001< 0.0010.211
Startle amplitude - BN /bw 1.08 ± 0.281.19 ± 0.310.86 ± 0.151.08 ± 0.230.050.0520.496
Startle amplitude - P1 /bw 2.24 ± 0.683.92 ± 2.381.77 ± 0.213.05 ± 0.740.0010.1190.643
Startle amplitude - P2 /bw 2.36 ± 0.714.32 ± 2.371.91 ± 0.384.09 ± 2.110.0010.5380.847
Startle amplitude - P3 /bw 2.9 ± 0.675.52 ± 2.892.36 ± 0.555.2 ± 2.54< 0.0010.5130.866
Startle amplitude - P4 /bw 5.58 ± 2.1712.7 ± 4.455.11 ± 1.699.47 ± 4.31< 0.0010.110.228
Media files
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