Selected project
Cldn12
Graphics
Graphic caption: B cell subsets: B-2 B cell subpopulations pie chart, split by sex and genotype
Graphic caption: B cell subsets: B/CD11b+ boxplot with stripchart, split by sex and genotype
Graphic caption: Immunglobulins: Concentration in blood plasma of female mice, boxplot, split by genotype
Graphic caption: Immunglobulins: Concentration in blood plasma of male mice, boxplot, split by genotype
Graphic caption: Main leukocyte populations: CD45+/CD11b+Ly6G+ boxplot with stripchart, split by sex and genotype
Graphic caption: Main leukocyte populations: CD45+/Ly6C+CD11b+ boxplot with stripchart, split by sex and genotype
Graphic caption: Main leukocyte populations: Frequencies of main leukocyte populations of female mice, boxplot, split by genotype
Graphic caption: Main leukocyte populations: Frequencies of main leukocyte populations of male mice, boxplot, split by genotype
Graphic caption: Main leukocyte populations: Leukocytes pie chart, split by sex and genotype
Graphic caption: Monocyte subsets: Monocyte pie chart, split by sex and genotype
Graphic caption: T cell subsets: CD4 T cell subpopulations pie chart, split by sex and genotype
Graphic caption: T cell subsets: CD4+/CD25+ boxplot with stripchart, split by sex and genotype
Graphic caption: T cell subsets: CD4+/Ly6C+ boxplot with stripchart, split by sex and genotype
Graphic caption: T cell subsets: CD8 T cell subpopulations pie chart, split by sex and genotype
Graphic caption: T cell subsets: T cell subpopulations pie chart, split by sex and genotype
Tables
Table caption: B cell subsets: B-2 B cell subpopulations (Boolean gates CD21,CD23, IgD, IgM). Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
femalemalefemalemaleoverall
 controlmutantcontrolmutant   
 n=15n=14n=15n=14   
 median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-valuep-valuep-value
B2/CD21+CD23+IgD+IgM+ 4.6
[2.19 , 6.16]
3.27
[1.79 , 4.92]
7.52
[5.64 , 10.95]
6.04
[3.31 , 6.76]
0.6130.1050.225
B2/CD21+CD23+IgD+IgM- 65.1
[62.55 , 69.7]
65.45
[64.03 , 67.35]
61.6
[59.05 , 64.8]
65.75
[61.35 , 70.92]
0.6830.1310.324
B2/CD21+CD23+IgD-IgM+ 0.29
[0.1 , 0.44]
0.2
[0.12 , 0.3]
0.36
[0.24 , 0.5]
0.3
[0.24 , 0.44]
0.3820.540.26
B2/CD21+CD23+IgD-IgM- 1.2
[0.94 , 1.34]
1.12
[0.93 , 1.3]
0.82
[0.68 , 1]
1
[0.87 , 1.09]
0.6590.1550.618
B2/CD21+CD23-IgD+IgM+ 1.43
[0.92 , 2]
1.3
[0.82 , 2.46]
2.9
[1.78 , 3.63]
2.48
[1.12 , 3.02]
0.9920.3540.47
B2/CD21+CD23-IgD+IgM- 2.83
[2.36 , 3.12]
3.33
[2.49 , 4.06]
2.43
[1.84 , 2.96]
3.04
[2.52 , 3.41]
0.2010.1310.049
B2/CD21+CD23-IgD-IgM+ 0.54
[0.21 , 0.73]
0.34
[0.18 , 0.46]
0.74
[0.38 , 0.79]
0.52
[0.32 , 0.72]
0.1610.3260.092
B2/CD21+CD23-IgD-IgM- 0.89
[0.77 , 1.21]
0.96
[0.82 , 1.05]
0.72
[0.6 , 1.06]
0.76
[0.65 , 0.92]
0.8720.8050.911
B2/CD21-CD23+IgD+IgM+ 0.8
[0.44 , 1.03]
0.86
[0.74 , 1.09]
1.43
[1.22 , 1.6]
1.02
[0.88 , 1.23]
0.540.0160.376
B2/CD21-CD23+IgD+IgM- 5.25
[4.51 , 8]
6.39
[5.02 , 8.04]
3.51
[2.84 , 4.72]
4.21
[3.36 , 5.94]
0.4770.2560.257
B2/CD21-CD23+IgD-IgM+ 0.21
[0.14 , 0.52]
0.18
[0.13 , 0.29]
0.42
[0.28 , 0.64]
0.38
[0.28 , 0.47]
0.3150.3710.152
B2/CD21-CD23+IgD-IgM- 2.3
[1.86 , 2.9]
2.38
[1.99 , 2.69]
1.83
[1.66 , 2.06]
1.83
[1.66 , 2.47]
0.9910.660.624
B2/CD21-CD23-IgD+IgM+ 0.69
[0.42 , 0.99]
0.69
[0.58 , 0.8]
1.61
[1.21 , 2.28]
1.15
[0.94 , 1.4]
0.9140.0260.208
B2/CD21-CD23-IgD+IgM- 1.82
[1.44 , 2.57]
2.39
[1.9 , 2.98]
1.76
[1.31 , 2.38]
1.88
[1.56 , 2.14]
0.0870.7550.154
B2/CD21-CD23-IgD-IgM+ 1.25
[0.55 , 2.63]
0.76
[0.45 , 1.4]
2.1
[1.14 , 3.09]
1.83
[1.18 , 2.22]
0.230.3160.098
B2/CD21-CD23-IgD-IgM- 7.96
[6.44 , 9.37]
7.91
[6.66 , 8.74]
6.75
[6.05 , 7.93]
6.51
[5.9 , 7.43]
0.8220.6830.868
Table caption: B cell subsets: Summary of total leukocyte count and B cells count
Table caption: Main leukocyte populations: Summary of total leukocyte count
Table caption: T cell subsets: Frequencies of CD4 and CD8 T cell subpopulations (Boolean gates CD44 high, CD62L, Ly6C). Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
femalemalefemalemaleoverall
 controlmutantcontrolmutant   
 n=15n=14n=15n=14   
 median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-valuep-valuep-value
4+/44++62L+6C+ 1.12
[0.94 , 2.41]
1.48
[1.14 , 2.04]
2.44
[2.15 , 2.65]
2.02
[1.68 , 2.35]
0.4060.0750.504
4+/44++62L+6C- 1.96
[1.61 , 2.25]
1.82
[1.33 , 2.25]
2.21
[1.62 , 2.76]
2.21
[1.93 , 2.65]
0.9740.9060.893
4+/44++62L-6C+ 3.05
[2.37 , 4.2]
2.92
[2.23 , 3.74]
3.05
[2.38 , 3.88]
2.89
[1.86 , 3.21]
0.8560.470.499
4+/44++62L-6C- 4.73
[3.19 , 4.92]
4.11
[3.15 , 4.79]
3.43
[3.15 , 4.54]
4.63
[3.96 , 5.09]
0.7710.050.305
4+/44-62L+6C+ 60
[54.25 , 67.2]
62.6
[57.1 , 70.05]
67.8
[65.7 , 72.75]
59.95
[56.65 , 61.83]
0.6210.0010.114
4+/44-62L+6C- 25.5
[19.55 , 30.9]
24.15
[19.12 , 28.43]
19
[13.75 , 20.6]
26.35
[23.77 , 27.7]
0.7390.0020.109
4+/44-62L-6C+ 2.1
[1.56 , 2.52]
1.74
[1.4 , 2.23]
0.77
[0.52 , 1.4]
1.66
[1.05 , 2.05]
0.4070.1020.554
4+/44-62L-6C- 0.9
[0.63 , 1.39]
0.9
[0.5 , 1.55]
0.47
[0.3 , 0.63]
0.88
[0.55 , 1.17]
0.9060.0220.1
8+/44++62L+6C+ 1.27
[1.15 , 1.75]
1.57
[1.12 , 1.86]
1.7
[1.57 , 2.42]
2.71
[1.72 , 3.33]
0.5610.2010.277
8+/44++62L+6C- 0.11
[0.05 , 0.2]
0.16
[0.11 , 0.21]
0.16
[0.1 , 0.2]
0.2
[0.1 , 0.28]
0.1850.3360.121
8+/44++62L-6C+ 0.08
[0.03 , 0.12]
0.04
[0.02 , 0.08]
0.1
[0.04 , 0.12]
0.06
[0.02 , 0.14]
0.5510.6730.408
8+/44++62L-6C- 0.03
[0 , 0.05]
0.03
[0 , 0.05]
0.03
[0 , 0.04]
0.03
[0 , 0.05]
0.7450.9730.801
8+/44-62L+6C+ 45.2
[42.2 , 52.35]
45.35
[42.45 , 58.35]
55.1
[54.35 , 62]
53.6
[50.02 , 55]
10.0750.514
8+/44-62L+6C- 51.3
[43.7 , 55.15]
51.1
[39.55 , 55.15]
38.8
[34.65 , 42.45]
42.6
[39.58 , 45.75]
0.9830.1090.519
8+/44-62L-6C+ 0.99
[0.7 , 1.42]
0.78
[0.47 , 0.92]
0.67
[0.54 , 1.19]
0.76
[0.58 , 1.07]
0.0710.6440.247
8+/44-62L-6C- 0.41
[0.31 , 0.51]
0.42
[0.18 , 0.57]
0.22
[0.16 , 0.36]
0.28
[0.16 , 0.34]
0.9740.7550.935
Table caption: T cell subsets: Summary of total leukocyte count and T cells count
Media files
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