Selected project
Hmgn1/Hmgn2
Graphics
Graphic caption: B cell subsets: B-2 B cell subpopulations class II pie chart, split by sex and genotype
Graphic caption: B cell subsets: MHC class II negative pie chart, split by sex and genotype
Graphic caption: B cell subsets: B-2 B cell subpopulations pie chart, split by sex and genotype
Graphic caption: B cell subsets: B/IgD+ boxplot with stripchart, split by sex and genotype
Graphic caption: B cell subsets: B/MHC2+ boxplot with stripchart, split by sex and genotype
Graphic caption: B cell subsets: IgD negative subpopulations pie chart, split by sex and genotype
Graphic caption: Main leukocyte populations: CD45+/NKTcells boxplot with stripchart, split by sex and genotype
Graphic caption: Main leukocyte populations: CD45+/NKcells boxplot with stripchart, split by sex and genotype
Graphic caption: Main leukocyte populations: CD45+/Tcells boxplot with stripchart, split by sex and genotype
Graphic caption: Main leukocyte populations: Frequencies of main leukocyte populations of female mice, boxplot, split by genotype
Graphic caption: Main leukocyte populations: Frequencies of main leukocyte populations of male mice, boxplot, split by genotype
Graphic caption: Main leukocyte populations: Leukocytes pie chart, split by sex and genotype
Graphic caption: Monocyte subsets: Monocyte pie chart, split by sex and genotype
Graphic caption: T cell subsets: CD4 T cell subpopulations pie chart, split by sex and genotype
Graphic caption: T cell subsets: CD8 T cell subpopulations pie chart, split by sex and genotype
Graphic caption: T cell subsets: T cell subpopulations pie chart, split by sex and genotype
Tables
Table caption: B cell subsets: B-2 B cell subpopulations (Boolean gates CD21,CD23, IgD, IgM). Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
femalemalefemalemaleoverall
 controlmutantcontrolmutant   
 n=15n=15n=15n=15   
 median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-valuep-valuep-value
B2/CD21+CD23+IgD+IgM+ 12.5
[8.71 , 15.85]
12.1
[7.94 , 15]
17.4
[11.6 , 29.85]
16.5
[10.02 , 19.35]
0.5740.340.356
B2/CD21+CD23+IgD+IgM- 64.2
[55.8 , 71.65]
67.2
[62.35 , 70]
60.2
[49.45 , 66.2]
59.7
[58.55 , 63.8]
0.3840.6750.246
B2/CD21+CD23+IgD-IgM+ 0.23
[0.11 , 0.4]
0.4
[0.26 , 0.62]
0.26
[0.18 , 0.4]
0.56
[0.38 , 0.82]
0.0650.0110.002
B2/CD21+CD23+IgD-IgM- 0.58
[0.4 , 0.7]
0.79
[0.72 , 0.87]
0.34
[0.3 , 0.52]
0.58
[0.49 , 0.83]
0.0070.0460.001
B2/CD21+CD23-IgD+IgM+ 2.2
[1.29 , 2.54]
1.48
[1.25 , 1.67]
1.6
[1.08 , 2.42]
2.24
[1.55 , 2.83]
0.140.4540.6
B2/CD21+CD23-IgD+IgM- 1.61
[1.3 , 2.18]
1.54
[0.96 , 1.87]
1.16
[0.66 , 1.37]
1.22
[0.84 , 1.58]
0.2670.3510.939
B2/CD21+CD23-IgD-IgM+ 0.24
[0.16 , 0.42]
0.42
[0.24 , 0.58]
0.26
[0.14 , 0.36]
0.57
[0.33 , 0.62]
0.1180.0230.006
B2/CD21+CD23-IgD-IgM- 0.4
[0.3 , 0.53]
0.42
[0.32 , 0.54]
0.25
[0.17 , 0.3]
0.3
[0.25 , 0.38]
0.830.0440.167
B2/CD21-CD23+IgD+IgM+ 2.36
[1.09 , 3.15]
1.27
[0.78 , 1.48]
2.57
[1.86 , 3.58]
1.64
[1.46 , 1.92]
0.0320.007< 0.001
B2/CD21-CD23+IgD+IgM- 2.66
[1.66 , 5.09]
1.83
[1.3 , 2.44]
2.59
[0.99 , 4]
1.47
[1.06 , 3.09]
0.1090.4540.078
B2/CD21-CD23+IgD-IgM+ 0.33
[0.18 , 0.7]
0.53
[0.42 , 0.95]
0.76
[0.36 , 1]
1.21
[0.66 , 1.46]
0.1290.0810.03
B2/CD21-CD23+IgD-IgM- 1.45
[1.2 , 1.94]
1.77
[1.45 , 2.23]
1.56
[1.06 , 1.9]
1.33
[1.2 , 2.58]
0.350.3090.217
B2/CD21-CD23-IgD+IgM+ 0.86
[0.62 , 1.17]
0.69
[0.37 , 0.8]
1.2
[0.96 , 1.95]
1.33
[0.68 , 1.74]
0.1510.5460.115
B2/CD21-CD23-IgD+IgM- 1.46
[0.94 , 2.31]
0.97
[0.68 , 1.4]
1.65
[1 , 1.96]
0.79
[0.67 , 1.47]
0.0910.0910.013
B2/CD21-CD23-IgD-IgM+ 1.05
[0.68 , 1.8]
1.62
[1.29 , 2.56]
1.91
[1.15 , 3.27]
3.28
[1.68 , 4.67]
0.1260.250.106
B2/CD21-CD23-IgD-IgM- 6.01
[4.37 , 8.37]
6.53
[4.95 , 8.55]
4.57
[4.04 , 6.62]
5.21
[4.45 , 7.54]
0.6530.3450.321
Table caption: T cell subsets: Frequencies of CD4 and CD8 T cell subpopulations (Boolean gates CD44 high, CD62L, Ly6C). Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
femalemalefemalemaleoverall
 controlmutantcontrolmutant   
 n=15n=15n=15n=15   
 median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-valuep-valuep-value
4+/44++62L+6C+ 3.44
[2.41 , 6.55]
4.17
[2.46 , 9.91]
4.64
[3.44 , 7.34]
3.28
[1.85 , 7.95]
0.480.4360.933
4+/44++62L+6C- 2.61
[1.01 , 4.02]
1.8
[1.04 , 3.36]
2.4
[0.88 , 4.44]
1.79
[0.08 , 2.75]
0.5120.250.171
4+/44++62L-6C+ 4.93
[2.12 , 8.17]
7.65
[4.49 , 11.65]
5.05
[3.23 , 8.18]
7.86
[3.73 , 9.82]
0.1090.4190.067
4+/44++62L-6C- 9.97
[7.12 , 13.45]
5.77
[2.92 , 11.7]
10.6
[5.08 , 12.1]
9.43
[3 , 11.95]
0.1610.7510.199
4+/44-62L+6C+ 47.4
[38.2 , 58.35]
45.5
[37.2 , 64.55]
51.2
[46.6 , 64.85]
36.1
[30.6 , 71.6]
0.9590.4120.356
4+/44-62L+6C- 18
[9.62 , 25.95]
13.4
[3.94 , 25.75]
19.1
[3.36 , 24.85]
19.6
[5.76 , 23.3]
0.6240.7210.574
4+/44-62L-6C+ 1.13
[0.4 , 9.54]
1.18
[0.48 , 17.05]
2.63
[1.35 , 7.08]
3.56
[2 , 14]
0.5320.2850.275
4+/44-62L-6C- 1.19
[0.3 , 5.78]
0.63
[0.2 , 4.64]
0.91
[0.66 , 2.25]
3.07
[0.36 , 8.3]
0.7750.340.875
8+/44++62L+6C+ 39.1
[30.95 , 42.5]
36.9
[30.15 , 53.6]
46.6
[41.05 , 49.55]
37.9
[29.85 , 45.5]
0.7130.0340.396
8+/44++62L+6C- 5.58
[1.46 , 8.94]
3.25
[1.42 , 7.2]
4.69
[1.1 , 8.54]
4.15
[0.54 , 7.04]
0.5120.5320.376
8+/44++62L-6C+ 8.99
[4.19 , 13]
9.6
[4.42 , 18.4]
8.51
[6.8 , 10.8]
8.1
[7.5 , 11.7]
0.4930.7750.451
8+/44++62L-6C- 1.81
[1.38 , 4.06]
0.76
[0.32 , 5.3]
2.46
[1.21 , 3.25]
3.45
[0.52 , 4.59]
0.8060.7750.869
8+/44-62L+6C+ 19.7
[14.5 , 25.8]
22.1
[17.3 , 26.45]
27.7
[18.45 , 31.25]
17.5
[13.75 , 38.45]
0.870.7210.589
8+/44-62L+6C- 9.37
[4.32 , 12.5]
5.63
[1.65 , 11.31]
8.74
[1.73 , 12.4]
11.4
[1.44 , 12.5]
0.2810.8940.615
8+/44-62L-6C+ 0.8
[0.28 , 6.07]
1.23
[0.25 , 9.43]
1.85
[0.98 , 4.25]
2.04
[0.79 , 6.45]
0.8140.7750.766
8+/44-62L-6C- 1.36
[0.84 , 6.87]
1.58
[0.76 , 7.62]
1.81
[1.1 , 2.76]
3.8
[0.78 , 11.03]
0.9020.2330.413
Media files
Media caption: Levels of Immunoglobulins in bloodplasma from female controls and mutants (microgram per mililiter)
Media caption: Levels of Immunoglobulins in bloodplasma from male controls and mutants (microgram per mililiter)