Selected project
Oplah / EPD0244_4_F09-tm1b
Graphics
Graphic caption: Echocardiography: LVIDd boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Heart rate Echo boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Respiration Rate Echo boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Left ventricular mass corrected boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Stroke Volume boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Aortic diameter boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Weight boxplot with stripchart, split by sex and genotype
Graphic:
Tables
Table caption: Echocardiography: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
control
mutant
control
mutant
n=10
n=8
n=13
n=8
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
IVSs [mm]
0.5
[0.48 , 0.53]
0.52
[0.52 , 0.54]
0.54
[0.52 , 0.55]
0.56
[0.52 , 0.59]
0.16
0.463
0.404
IVSd [mm]
0.51
[0.49 , 0.54]
0.54
[0.54 , 0.56]
0.54
[0.51 , 0.57]
0.52
[0.5 , 0.59]
0.117
0.927
0.36
LVPWs [mm]
0.55
[0.51 , 0.56]
0.56
[0.54 , 0.58]
0.54
[0.53 , 0.54]
0.55
[0.53 , 0.59]
0.256
0.416
0.127
LVPWd [mm]
0.52
[0.5 , 0.54]
0.52
[0.5 , 0.55]
0.53
[0.5 , 0.54]
0.55
[0.53 , 0.56]
0.981
0.532
0.706
LVIDs [mm]
1.09
[0.91 , 1.23]
1.27
[1.02 , 1.5]
1.21
[1.1 , 1.42]
1.38
[1.03 , 1.52]
0.173
1
0.502
LVIDd [mm]
2.48
[2.34 , 2.53]
2.7
[2.54 , 2.99]
2.53
[2.46 , 2.94]
2.9
[2.54 , 2.96]
0.017
0.804
0.091
Weight [g]
20.8
[20.4 , 21.6]
23.5
[22.3 , 23.9]
26.6
[25.5 , 28.5]
25.7
[23.8 , 28.2]
0.002
0.489
0.567
Heart rate Echo [bpm]
691.07
[659.42 , 712.21]
545.7
[510.25 , 580.96]
658.09
[609.51 , 686.63]
648.31
[633.46 , 682.87]
0.003
0.75
0.02
Respiration Rate Echo [1/min]
250.03
[232.03 , 266.67]
186.78
[163.55 , 202.18]
188.98
[169.01 , 206.9]
272.87
[233.54 , 292.2]
0.015
0.056
0.961
Fractional shortening [percent]
56.49
[53.68 , 64.92]
57.84
[55.38 , 64.25]
55.68
[50.76 , 60.03]
57.19
[52.01 , 60.24]
0.762
0.414
0.404
Ejection fraction [percent]
88.36
[86.24 , 93.54]
88.94
[86.92 , 93.03]
87.16
[83.51 , 90.87]
88.52
[84.46 , 90.57]
0.897
0.547
0.507
Left ventricular mass corrected [mg]
20.19
[17.62 , 22.89]
26.45
[25.29 , 30.83]
25.77
[20.46 , 29.46]
25.71
[22.45 , 29.05]
0.006
0.846
0.051
Stroke Volume [mul]
19.73
[17.71 , 22.75]
28.39
[26.02 , 32.56]
22.24
[18.47 , 27.78]
27.95
[21.43 , 28.1]
0.002
0.697
0.024
Cardiac output [ml/min]
14.122
[12.065 , 15.796]
14.061
[13.69 , 16.799]
14.572
[13.162 , 19.212]
18.299
[13.636 , 19.476]
0.408
0.804
0.525
Aortic diameter [mm]
1.17
[1.09 , 1.25]
1.3
a
[1.24 , 1.36]
1.31
a
[1.25 , 1.37]
1.28
[1.08 , 1.29]
0.02
0.085
0.86
Table caption: Electrocardiography: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
control
mutant
control
mutant
n=10
n=8
n=14
n=8
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
Heart Rate [bpm]
790
[764 , 809]
785
[770 , 796]
762
[752 , 773]
760
[735 , 778]
0.984
0.907
0.865
Heart Rate Variability [bpm]
7.9
[5.7 , 22.3]
6.2
[4.4 , 13.2]
6.1
[3.2 , 9.2]
10.9
[4 , 24.4]
0.696
0.482
0.738
RR [ms]
76
[74.2 , 78.6]
76.6
[75.5 , 78]
78.8
[77.6 , 79.8]
79
[77.2 , 81.8]
0.965
0.881
0.94
PQ [ms]
21.3
[19.2 , 23.9]
22
[20.4 , 24]
22.1
[21.1 , 25]
22.7
[21.4 , 24.4]
0.965
0.828
0.728
PR [ms]
26.8
[26 , 29.8]
27.6
[26.1 , 29.2]
28.6
[27 , 30.9]
29.4
[28.8 , 30.6]
0.896
0.431
0.507
QRS [ms]
9.7
[9 , 10.2]
9.8
[9.2 , 10.6]
9.7
[8.9 , 10.2]
9.9
[9.8 , 10.4]
0.712
0.14
0.171
QT [ms]
38.8
[37.4 , 39.6]
38.1
[36.5 , 39.2]
38.1
[37.9 , 39.2]
39.3
[36.9 , 41.2]
0.499
0.802
0.801
ST [ms]
29.4
[27.2 , 31.8]
28.5
[26.9 , 30.4]
29.6
[28.9 , 30.5]
29.9
[27.9 , 31.7]
0.446
0.881
0.628
QTc [ms]
44.1
[42.9 , 46.1]
44.4
[41.5 , 45.1]
43
[42.6 , 44.6]
44.8
[41.9 , 46.7]
0.528
0.628
0.951
QT dispersion [ms]
20
[16.5 , 21.6]
20.2
[17.8 , 22.2]
19.8
[18.1 , 23.4]
19.8
[17.9 , 22]
0.778
0.828
0.973
QTc dispersion [ms]
21.8
[18.9 , 23.6]
22.4
[20.1 , 24.6]
22.1
[20.7 , 26.5]
21.8
[19.6 , 24.1]
0.633
0.493
0.822
mean SR amplitude [mV]
1.18
[0.98 , 1.48]
1.6
[1.37 , 1.9]
1.13
[0.92 , 1.71]
0.55
[0.36 , 1.21]
0.083
0.035
0.811
mean R amplitude [mV]
0.9
[0.62 , 1.03]
1.21
[1.05 , 1.36]
0.91
[0.75 , 1.21]
0.42
[0.23 , 0.9]
0.055
0.048
0.919
Media files
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