Selected project
Fam216a / HEPD0675_7_F06-tm1b
Graphics
Graphic caption: OCT: left fundus number of main vessels boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: OCT: right fundus number of main vessels boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: OCT: left retinal thickness boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: OCT: right retinal thickness boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Anterior Eye Investigation: mean(lens density left eye) boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Anterior Eye Investigation: mean(lens density right eye) boxplot with stripchart, split by sex and genotype
Graphic:
Tables
Table caption: OCT: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
control
mutant
control
mutant
n=22
n=7
n=24
n=8
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
left fundus number of main vessels [#]
10
[9 , 10]
9
[8 , 10]
11
[9 , 12]
9
[9 , 10]
0.546
0.029
0.038
right fundus number of main vessels [#]
9
[9 , 10]
10
[8 , 10]
10
[9 , 10]
10
[9 , 10]
0.608
0.914
0.82
left retinal thickness [mum]
253
[249 , 257]
246
[243 , 248]
250
[248 , 255]
243
[236 , 246]
0.01
< 0.001
< 0.001
right retinal thickness [mum]
249
[244 , 254]
250
[242 , 252]
250
[246 , 252]
246
[239 , 247]
0.702
0.06
0.105
Table caption: Anterior Eye Investigation: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
control
mutant
control
mutant
n=22
n=7
n=24
n=8
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
max(lens density left eye)
10.8
[7.8 , 12.1]
7.8
[7.1 , 8.8]
9.8
[7.1 , 11.8]
8
[6.7 , 10.7]
0.059
0.349
0.038
mean(lens density left eye)
6.9
[6.3 , 8.3]
5.6
[5.3 , 5.8]
6.8
[5.8 , 8.3]
6
[5.7 , 7.8]
0.002
0.35
0.006
max(lens density right eye)
9.8
[7.8 , 11.4]
7.1
[7.1 , 7.7]
8.8
[7.4 , 10.6]
9.4
[7.5 , 11.6]
0.018
0.773
0.169
mean(lens density right eye)
8.2
[6.5 , 8.6]
6
[5.9 , 6.3]
7
[6.3 , 8.4]
7.3
[6.2 , 8.8]
0.016
0.741
0.162
Table caption: Eye morphology: Results morphological observation of the eyes
Table:
Female
Male
Female
Male
Control
Mutant
Control
Mutant
n=22
n=7
n=24
n=8
p value
1
p value
2
Lens
0.04099
0.31603
both eyes abnormal
10
0
12
2
left eye abnormal
1
1
3
1
normal
8
6
8
3
right eye abnormal
3
0
1
2
Lens Opacity
0.04099
0.31603
absent
8
6
8
3
present both eyes
10
0
12
2
present left eye
1
1
3
1
present right eye
3
0
1
2
Persistence of hyaloid vascular system
0.65959
0.02423
absent
18
7
20
4
no data for both eyes
1
0
0
0
present both eyes
0
0
0
3
present left eye
0
0
2
0
present right eye
3
0
2
1
Media files
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