Selected project
Il4i1 / EPD0369_7_D03-tm1b
Graphics
Graphic caption: Echocardiography: LVIDd boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: LVIDs boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Heart rate Echo boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: IVSs boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Ejection fraction boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Fractional shortening boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Echocardiography: Stroke Volume boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Electrocardiography: Heart Rate boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Electrocardiography: RR boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Electrocardiography: PR boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Electrocardiography: QT boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Electrocardiography: QTc boxplot with stripchart, split by sex and genotype
Graphic:
Graphic caption: Electrocardiography: P boxplot with stripchart, split by sex and genotype
Graphic:
Tables
Table caption: Echocardiography: Mean and standard deviation, split by sex and genotype
Table:
female
male
con
mut
con
mut
n=10
n=10
n=9
n=9
mean ± sd
mean ± sd
mean ± sd
mean ± sd
IVSs [mm]
0.56 ± 0.03
0.55 ± 0.04
0.59 ± 0.03
0.56 ± 0.03
IVSd [mm]
0.56 ± 0.02
0.56 ± 0.02
0.58 ± 0.02
0.57 ± 0.02
LVPWs [mm]
0.55 ± 0.02
0.54 ± 0.03
0.57 ± 0.03
0.54 ± 0.02
LVPWd [mm]
0.55 ± 0.02
0.55 ± 0.01
0.55 ± 0.03
0.54 ± 0.02
LVIDs [mm]
1.08 ± 0.32
1.49 ± 0.36
1.31 ± 0.22
1.42 ± 0.38
LVIDd [mm]
2.36 ± 0.36
2.73 ± 0.29
2.7 ± 0.27
2.86 ± 0.44
Weight [g]
23.8 ± 1.9
23.9 ± 2.7
28.1 ± 2.3
28.1 ± 2.9
Heart rate Echo [bpm]
696.07 ± 55.87
581.8 ± 100.19
671.21 ± 106.75
587.68 ± 103.17
Respiration Rate Echo [1/min]
216.28 ± 39.57
199.17 ± 38.71
228.17 ± 40.22
203.62 ± 25.68
Fractional shortening [percent]
58.27 ± 7.35
49.18 ± 6.2
54.84 ± 5.48
50.25 ± 6.39
Ejection fraction [percent]
89.05 ± 5.52
81.63 ± 6.18
86.64 ± 4.36
82.41 ± 6.57
Left ventricular mass corrected [mg]
32.76 ± 8.4
38.91 ± 7.09
41.12 ± 5.2
42.27 ± 9.78
Stroke Volume [mul]
18.7 ± 5.19
23.99 ± 5.43
22.82 ± 3.51
26.92 ± 6.94
Cardiac output [ml/min]
12.954 ± 3.624
13.845 ± 3.135
15.24 ± 3.072
15.245 ± 1.072
Aortic diameter [mm]
1.26 ± 0.07
1.24 ± 0.08
a
1.31 ± 0.13
1.31 ± 0.1
Table caption: Echocardiography: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
con
mut
con
mut
n=10
n=10
n=9
n=9
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
IVSs [mm]
0.57
[0.56 , 0.58]
0.55
[0.52 , 0.57]
0.58
[0.57 , 0.59]
0.57
[0.55 , 0.58]
0.22
0.063
0.044
IVSd [mm]
0.56
[0.55 , 0.58]
0.56
[0.54 , 0.57]
0.57
[0.57 , 0.59]
0.57
[0.56 , 0.58]
0.787
0.647
0.57
LVPWs [mm]
0.55
[0.53 , 0.56]
0.54
[0.52 , 0.57]
0.57
[0.55 , 0.58]
0.55
[0.54 , 0.55]
0.78
0.115
0.211
LVPWd [mm]
0.55
[0.53 , 0.56]
0.55
[0.54 , 0.56]
0.54
[0.54 , 0.57]
0.54
[0.53 , 0.55]
0.762
0.442
0.679
LVIDs [mm]
1.03
[0.9 , 1.09]
1.48
[1.23 , 1.68]
1.38
[1.14 , 1.5]
1.29
[1.26 , 1.63]
0.014
0.651
0.027
LVIDd [mm]
2.3
[2.12 , 2.58]
2.8
[2.47 , 2.88]
2.7
[2.5 , 2.9]
2.71
[2.68 , 2.85]
0.015
0.62
0.047
Weight [g]
23.3
[22.4 , 24.2]
24.2
[22.9 , 25.2]
29
[28.6 , 29.5]
28.1
[27.5 , 30.2]
0.617
0.776
0.902
Heart rate Echo [bpm]
702.67
[663.45 , 725.29]
608.98
[514.61 , 643.48]
695.6
[628.54 , 740.44]
618.13
[559.44 , 638.57]
0.004
0.063
0.001
Respiration Rate Echo [1/min]
203.53
[193.59 , 228.63]
198.36
[185.71 , 216.42]
240
[193.55 , 247.42]
208.7
[190.48 , 222.22]
0.517
0.081
0.14
Fractional shortening [percent]
60.23
[53.39 , 62.61]
50.8
[44.61 , 54.02]
56.52
[51.12 , 58.45]
53.05
[45.05 , 53.93]
0.015
0.19
0.004
Ejection fraction [percent]
90.79
[86.36 , 92.61]
83.55
[77.57 , 86.65]
88.24
[83.91 , 89.58]
85.62
[77.86 , 86.32]
0.009
0.19
0.003
Left ventricular mass corrected [mg]
32.87
[27.09 , 35.37]
41.02
[33.9 , 43.45]
41.23
[38.09 , 43.87]
38.87
[37.06 , 42.71]
0.143
0.436
0.354
Stroke Volume [mul]
19.48
[15.25 , 21.13]
24.25
[20.73 , 26.75]
24.04
[19.67 , 24.38]
24.84
[23.06 , 28.04]
0.075
0.258
0.025
Cardiac output [ml/min]
12.681
[10.525 , 15.344]
14.318
[12.558 , 15.73]
14.901
[12.994 , 18.049]
15.592
[14.726 , 15.836]
0.579
1
0.644
Aortic diameter [mm]
1.25
[1.23 , 1.3]
1.24
a
[1.23 , 1.27]
1.3
[1.26 , 1.37]
1.31
[1.25 , 1.36]
0.703
1
0.793
Table caption: Electrocardiography: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
con
mut
con
mut
n=10
n=10
n=9
n=9
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
Heart Rate [bpm]
769
[763.3 , 779.4]
764
[754.5 , 771.5]
778.5
[763.1 , 798.2]
738.3
[735.2 , 748.3]
0.353
0.05
0.032
RR [ms]
78
[77 , 78.6]
78.5
[77.8 , 79.5]
77.1
[75.2 , 78.6]
81.3
[80.2 , 81.6]
0.306
0.047
0.028
PR [ms]
32.2
[30.7 , 33.1]
32.5
[31.8 , 33]
30.5
[30.2 , 31]
33.7
[33 , 33.8]
0.54
0.033
0.011
QRS [ms]
12.8
[12.3 , 13.2]
12.2
[11.7 , 12.6]
13
[12.9 , 15.7]
13.1
[12 , 13.8]
0.305
0.449
0.209
QT [ms]
19.4
[18.8 , 20.1]
20.6
[20.1 , 21]
20
[19.2 , 22.2]
19.4
[19.1 , 20.7]
0.007
0.422
0.405
QTc [ms]
70.2
[67.3 , 72.2]
73.6
[71.9 , 74.8]
70.9
[68.3 , 79.4]
69.4
[67.1 , 71.5]
0.02
0.34
0.618
QT dispersion [ms]
1.4
[0.9 , 1.5]
0.9
[0.4 , 1.5]
1
[0.5 , 3]
0.4
[0.3 , 1.2]
0.322
0.286
0.135
QTc dispersion [ms]
4.8
[3.3 , 5.4]
4.2
[1.3 , 4.6]
3.6
[1.7 , 10.8]
1.5
[1 , 4.5]
0.324
0.248
0.156
P [ms]
11.6
[10.9 , 12.4]
12.8
[12.1 , 13.5]
10.3
[10.2 , 12.8]
12.9
[11.1 , 13.3]
0.148
0.168
0.044
Table caption: Electrocardiography: Mean and standard deviation, split by sex and genotype
Table:
female
male
con
mut
con
mut
n=10
n=10
n=9
n=9
mean ± sd
mean ± sd
mean ± sd
mean ± sd
Heart Rate [bpm]
769.4 ± 18.4
763.2 ± 12.1
775.4 ± 23.9
747.8 ± 29
RR [ms]
78 ± 1.9
78.7 ± 1.2
77.5 ± 2.4
80.3 ± 3.1
PR [ms]
31.9 ± 1.4
32.4 ± 0.9
30.4 ± 1.4
32.7 ± 2.6
QRS [ms]
12.7 ± 1
12.2 ± 1.1
13.9 ± 1.9
13.1 ± 1.4
QT [ms]
19.4 ± 1.2
20.6 ± 0.7
20.4 ± 2.4
19.6 ± 1.2
QTc [ms]
69.4 ± 4.2
73.5 ± 2.5
73.4 ± 8.4
69.2 ± 3.6
QT dispersion [ms]
1.3 ± 0.7
1 ± 0.7
1.5 ± 1.5
0.7 ± 0.7
QTc dispersion [ms]
4.6 ± 2.6
3.4 ± 2.2
5.6 ± 5.3
2.7 ± 2.7
P [ms]
11.9 ± 1.4
12.8 ± 1.4
11.1 ± 1.7
12.5 ± 2.3
Media files
No records found.