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Dis3 / HEPD0659_5_E08-tm1b
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Tables
Table caption: Echocardiography: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
control
mutant
control
mutant
n=7
n=7
n=8
n=8
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
IVSs [mm]
0.54
[0.5 , 0.56]
0.52
[0.5 , 0.55]
0.54
[0.53 , 0.55]
0.54
[0.5 , 0.57]
0.513
0.929
0.504
IVSd [mm]
0.52
[0.5 , 0.54]
0.52
[0.51 , 0.54]
0.54
[0.51 , 0.57]
0.55
[0.53 , 0.56]
0.617
1
0.765
LVPWs [mm]
0.57
[0.56 , 0.6]
0.56
[0.55 , 0.57]
0.56
[0.56 , 0.57]
0.57
[0.54 , 0.58]
0.439
0.693
0.702
LVPWd [mm]
0.54
[0.54 , 0.57]
0.57
[0.54 , 0.57]
0.55
[0.54 , 0.56]
0.56
[0.55 , 0.57]
0.804
0.239
0.273
LVIDs [mm]
1.2
[0.92 , 1.53]
1.43
[1.12 , 1.58]
1.32
[1.15 , 1.62]
1.33
[1.15 , 1.38]
0.535
0.82
0.846
LVIDd [mm]
2.46
[2.32 , 2.83]
2.74
[2.46 , 2.88]
2.61
[2.36 , 2.92]
2.71
[2.58 , 2.8]
0.558
0.591
0.406
Weight [g]
24
[23.7 , 24.4]
21.2
[20 , 22.1]
29.9
[29.1 , 30.8]
26.9
[25.4 , 29.1]
0.016
0.05
0.104
Heart rate Echo [bpm]
660.6
[621.88 , 673.2]
690.74
[615.88 , 741.49]
703
[570.02 , 722.5]
728.14
[701.94 , 744.4]
0.318
0.279
0.098
Respiration Rate Echo [1/min]
228.57
[217.74 , 243.71]
190.48
[169.43 , 211.11]
222.4
[209.5 , 258.9]
220.26
[190.16 , 240.69]
0.079
0.521
0.095
Fractional shortening [percent]
58.82
[51.95 , 63.47]
50.53
[47.96 , 61.21]
52.22
[48.32 , 55.73]
53.48
[50.88 , 60.11]
0.805
0.574
0.967
Ejection fraction [percent]
89.89
[84.06 , 92.72]
83.39
[80.7 , 91.64]
84.72
[81 , 87.63]
85.83
[83.73 , 90.5]
0.805
0.721
0.935
Left ventricular mass corrected [mg]
28.26
[24.72 , 31.29]
28.82
[26.61 , 34.4]
34.1
[29.95 , 37.2]
32.2
[30.69 , 38.28]
0.535
0.959
0.683
Stroke Volume [mul]
19.99
[18.54 , 27.43]
24.39
[20.66 , 26.22]
24.32
[21.26 , 25.8]
23.86
[22.18 , 26.72]
0.902
0.721
0.683
Cardiac output [ml/min]
13.736
[12.469 , 17.047]
16.659
[14.367 , 17.541]
15.203
[13.752 , 17.583]
17.956
[16.315 , 19.416]
0.62
0.195
0.187
Aortic diameter [mm]
1.26
[1.25 , 1.28]
1.22
[1.16 , 1.25]
1.32
[1.31 , 1.4]
1.36
[1.27 , 1.44]
0.194
0.941
0.492
Table caption: Electrocardiography: Medians, first and third quartile and p-values calculated by a Wilcoxon rank-sum test$\^{a}$ Number not based on the full number of animals (missing values)
Table:
female
male
female
male
overall
control
mutant
control
mutant
n=7
n=7
n=8
n=8
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
median
[25%, 75%]
p-value
p-value
p-value
Heart Rate [bpm]
768
[762 , 792]
776
[772 , 787]
804
[770 , 821]
772
[762 , 778]
0.596
0.098
0.361
Heart Rate Variability [bpm]
19.2
[15.8 , 30.8]
11.7
[4 , 15.6]
6
[4.5 , 7.8]
5.2
[3.5 , 6.5]
0.073
0.556
0.109
RR [ms]
78.3
[75.8 , 78.9]
77.3
[76.2 , 77.7]
74.6
[73 , 78]
77.8
[77.2 , 78.8]
0.596
0.098
0.372
PQ [ms]
21.1
[20.1 , 23.9]
20.7
[18 , 24.1]
19.9
[18.3 , 21.1]
21.2
[18.8 , 23.7]
0.737
0.626
1
PR [ms]
26.8
[25.6 , 30.4]
27.5
[24.4 , 30.1]
26.7
[24.9 , 27.6]
27
[24.4 , 30]
0.71
0.626
0.911
QRS [ms]
9.8
[8.7 , 10.2]
10.5
[9.9 , 10.7]
10.3
[10 , 11.2]
10.1
[9.5 , 10.2]
0.176
0.15
0.927
QT [ms]
39.6
[35.5 , 40.5]
39
[38 , 39.8]
38.5
[36.8 , 40]
36.9
[35.9 , 39]
1
0.342
0.69
ST [ms]
29.5
[27.4 , 31.5]
28.8
[28.1 , 29.6]
28.9
[26.8 , 29.9]
27.6
[26.3 , 29.5]
0.902
0.721
0.675
QTc [ms]
44.9
[40 , 45.8]
44.5
[43.2 , 45.1]
45.2
[41.6 , 46.5]
41.6
[40.6 , 44.5]
0.875
0.185
0.442
QT dispersion [ms]
22
[19.5 , 24.2]
19
[17.8 , 19.8]
19.2
[13.4 , 20.2]
23
[20.8 , 24.1]
0.206
0.013
0.441
QTc dispersion [ms]
25.2
[21.1 , 26.4]
21.2
[20.4 , 22.6]
22.4
[15.6 , 23.2]
26.2
[23.4 , 27.3]
0.259
0.038
0.454
mean SR amplitude [mV]
1.4
[1.04 , 1.66]
1.37
[1.29 , 1.8]
1.14
[0.98 , 1.52]
1.25
[1.06 , 1.72]
0.535
0.398
0.245
mean R amplitude [mV]
0.83
[0.74 , 1.14]
0.97
[0.92 , 1.2]
0.72
[0.6 , 1.09]
0.84
[0.76 , 1.25]
0.245
0.291
0.164
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